All the information you need ahead of Saturday's clash between two Premier League heavyweights at the Etihad Stadium.
Antonio Conte's Blues have won their last seven Premier League games, with Christian Eriksen's great strike for Tottenham last weekend the only goal they have conceded during that impressive run.
City are unbeaten in six matches themselves and have won their last two, including the hard-fought 2-1 win at Burnley last time out that showed any doubters that Pep Guardiola's side can battle their way through tough matches.
Manchester City's Kevin De Bruyne celebrates scoring their second goal
The Key Battle - Kevin De Bruyne vs N'golo Kante
The Belgian attacking midfielder will be desperate to prove a point against his former club, and whether he plays on the wing or in the centre he is likely to have a big impact on the outcome.
Trying to stop him in his tracks will be Kante, whose ball-winning skills will be crucial in the middle of the park against City's array of talented midfield players.
Chelsea's N'Golo Kante
Manchester City won both league matches against Chelsea by a 3-0 scoreline last season, with the most recent of those being inspired by a Sergio Aguero hat-trick in April's meeting at Stamford Bridge.
Overall, Chelsea have won 62 of these matches, City have 52 victories to their name and there have been 39 draws.
Chelsea's Pedro in action with Manchester City's Pablo Zabaleta
Recent league form – most recent last:
Manchester City - DDWDWW
Chelsea - WWWWWW
Who’s the ref?
Anthony Taylor will be the man in the middle at the Etihad.
Taylor has overseen 16 games this season and is yet to show a red card. He has also taken charge of Chelsea on two occasions in this campaign so far - the 2-1 opening weekend win over West Ham and the 2-0 success at Hull.
Rferee Anthony Taylor (L)
What time is kick off?
Manchester City v Chelsea begins at 12.30pm on Saturday.
Where can I watch it?
Sky Sports 1 are showing this one live, with build-up getting underway at 11.30am.
Manchester City - 11/10
Draw - 5/2
Chelsea - 12/5