Liverpool and Hull City both booked their places in the semi-finals of the EFL Cup on Tuesday night, beating Leeds United and Newcastle United respectively.
Arsenal manager Arsene Wenger
Now, Arsenal and Southampton lock horns at the Emirates Stadium with a place in the last four of the competition up for grabs, and both are coming into the game off the back of Premier League wins.
Arsenal beat Southampton 3-1 at the Emirates Stadium, whilst Southampton picked up an impressive 1-0 home win over Everton on Sunday evening.
Tonight, the two two sides meet again, as Arsenal beat Southampton 2-1 in the Premier League earlier this season, with Santi Cazorla's injury-time penalty grabbing the Gunners a fortunate victory.
Southampton manager Claude Puel
The game will also see old friends Arsene Wenger and Claude Puel go head-to-head, with the two French managers no strangers to each other having worked together at Monaco.
Now, pundit Charlie Nicholas has discussed the game, telling Sky Sports that he thinks Arsenal will run out 3-2 winners in a close-run, high-scoring encounter.
Nicholas thinks it's an awkward game for Arsenal, with Puel no doubt looking for a result against Wenger, but thinks the quality of rotation will be the key factor, as Arsenal can bring in better players than Southampton can.
General view of the Emirates Stadium
“Well this is an awkward one for Arsenal,” said Nicholas. “They were lucky in the league meeting to beat Southampton, who recorded a very good result on Sunday. I do think the Saints will make changes which will make them weaker, although I'm sure Claude Puel would love a result against his good friend Arsene Wenger.”
“You look at the players Arsenal can bring in and Aaron Ramsey can come in, Alex Iwobi can come in. The difference in the quality of players coming in will be decisive for me here and I think Arsenal will be able to end November with a win,” he added.
What's your prediction for Arsenal v Southampton?