Chelsea and Tottenham go head-to-head with last year's Battle of Stamford Bridge still fresh in the memory.
Tottenham's Eric Dier fouls Chelsea's Eden Hazard
Fireworks will fly on Saturday evening, with two title and London rivals in very differing form doing battle once more.
Chelsea vs Tottenham has always guaranteed goals and last season was probably the most memorable encounter between the two teams.
Spurs travelled to Chelsea knowing they had to win to have any hope of catching Leicester City, but in a tempestuous and feisty affair, they let a two-goal lead slip to draw and hand The Foxes the title, much to the delight of the majority of Stamford Bridge.
This season, Chelsea are finally righting their wrongs and Antonio Conte's side lead the way at the top of the table, but it's all gone wrong for Spurs in recent weeks culminating in their disastrous defeat to Monaco and early exit from the Champions League.
With a terrible record at Stamford Bridge and just one win in nine games, Tottenham are firmly up against it with The Blues confident they can inflict more misery on the visitors and increase the pressure on Mauricio Pochettino.
But where will the match be won and lost for both sides? Here are three key battles to watch out for.
Tottenham's Eric Dier and Chelsea's Diego Costa in action
Diego Costa vs Eric Dier
The Premier League's top scorer is back to his very best and his insistence on playing on the very edge is something Eric Dier needs to watch out for.
Costa has a habit of winding people up the wrong way and with Dier losing his head in last season's fixture, fouling everybody in sight, sparks will fly between the two again.
The England international has looked incredibly shaky at centre back and Costa will look to take advantage of his poor form.
Tottenham's Victor Wanyama in action with Arsenal's Granit Xhaka
N'Golo Kante vs Victor Wanyama
Two of the league's most in-form defensive midfielders butt heads in West London and their importance to their respective sides cannot be underestimated.
N'Golo Kante protects Chelsea's back three alongside Nemanja Matic while Victor Wanyama sits deepest in a 4-1-4-1 system for Tottenham.
Take them both out of the equation and that's when trouble starts to brew and their defensive discipline is vital to their team's chances of taking something out of the weekend's clash.
Chelsea's Eden Hazard in action with Tottenham's Kyle Walker
Eden Hazard vs Kyle Walker
Eden Hazard looks a different person compared to last season with the classy winger netting seven times in 12 league games.
He comes up against Kyle Walker who was controversially left out of Spurs' game against Monaco which proved to be a fatal decision.
All attacks are set to go through those two on Saturday. Walker's width is vital to Tottenham's attack and with Hazard free of defensive responsibility in Conte's system, the Chelsea winger will have to curtail the Spurs full-back and vice-versa.
Tottenham's Ryan Mason clashes with Chelsea's Diego Costa