Sheffield Wednesday will be without striker Gary Hooper after the goal-getter suffered an injured hamstring during last weekend's 1-1 draw with Fulham.
Considering that Hooper has ben involved in almost 85% of Wednesday's goals in October and November (three goals, two assists), the absence of the former Celtic and Norwich City striker could be decisive for this match.
Owls' boss Carlos Carvalhal is likely to call upon former Wolves forward Steven Fletcher as Hooper's replacement, with the Scotland international expected to be paired with the deeper lying Fernando Forestieri in attack.
Behind the front two, Carvalhal is likely to deploy Adam Reach on the left and Ross Wallace on the right of a four man midfield. The central roles are expected to be filled by Kieran Lee and another former Wolves man, David Jones.
Wednesday's defensive unit should see changes to the back four that faced Fulham last time out. Despite being linked with Championship competitors Aston Villa, Goalkeeper Kieran Westwood remains, but with only centre back and captain Tom Lees.
Lees could be partnered in central defence by Sam Hutchinson, who has also been deployed in a midfield role of late, with the full back positions possibly being afforded to Liam Palmer on the right and the returning Daniel Pudil on the left.
Pudil's return from injury would mean that Barry Bannan drops to the bench with Adam Reach moving out of the back line, whereas defender Jack Hunt may continue his two game run in the side - but Palmer is just as likely to take the right back slot for this one.
Here's the predicted Sheffield Wednesday line-up in full.