The Frenchman isn't taking The Gunners' position at the top of Group A for granted when they host the Bulgarians on Wednesday.
The Gunners are currently in pole position of Group A level on points with Paris Saint-Germain and face back-to-back games against Ludogorets starting at the Emirates on Wednesday.
In a group also containing FC Basel, qualification to the knockout stage of the competition is almost a certainty but they face a battle for top spot with PSG who are also expected to make their way past the group stage.
Chelsea's Diego Costa in action with Arsenal's Francis Coquelin
The opportunity to stay ahead of the French side is not lost on Coquelin who could return to Arsene Wenger's side after overcoming his knee injury, but the Frenchmandoesn't see the visit of the Bulgarian champions as a game to take lightly.
"It’s a massive game, especially as it is at home," he said in the pre-match press conference. "We know we’re going to have two more tough games away too, against Ludogorets and Basel, plus a home game against Paris Saint-Germain.
"So it’s massively important to get the three points on Wednesday."
Coquelin faces a fight with Mohamed Elneny and Granit Xhaka for a spot alongside Santi Cazorla as the holding midfielder, but Xhaka's red card against Swansea City last weekend could hand the 25-year-old a start against Middlesbrough on Saturday.
Leicester City's Jamie Vardy in action with Arsenal's Francis Coquelin
His injury in the 3-0 win against Chelsea last month was a worry for Coquelin after his tackle forced him to be taken off, but he's happy that no lasting damage was done on returning to full fitness.
"When you make these kinds of tackles, and this happened before against West Brom [last season], you are a bit scared," he said.
"It was a similar tackle to then. The good thing was that I could run back on to the pitch afterwards, even if I couldn’t stay on for long.
"The scan which followed was all positive so that was great news. It took me a few weeks to get back to full fitness, but now I feel good."
Arsenal's Francis Coquelin receives medical attention after sustaining a injury