Grealish missed Aston Villa's win at Reading - their first under their new manager.
As well as Tuesday's victory at Reading, which saw Villa win for the first time away from home since August 2015, Grealish will miss the upcoming fixtures against Fulham and Birmingham City following an incident with Wolves' Conor Coady on Saturday.
"I feel as if he's been a bit hard done by," Bruce said after his first win in charge of Aston Villa. "I think it's because it's Jack Grealish.
"It's something (about which) I'll have a conversation with (Grealish), because unfortunately we're talking about him in the wrong situation. We should be talking about his football - he was our best player on Saturday."
Bruce conceded that if it is established that Grealish did "something silly", he will ensure that the England Under-21 international "cuts out" that sort of behaviour in future.
It would not be the first time the Aston Villa product has become involved in controversy - something which prompted a comparison to be made by the BBC reporter, between Grealish and Eric Cantona, who was a teammate of Bruce at Manchester United.
"The big difference is Cantona had been there, done it, wore the t-shirt," the 56-year-old intervened. "Jack hasn't quite yet, so in that respect we've got to try and protect him, help him, nurture him along, because he has got a talent, we all know that, and that's why we're talking about him."
Goals from Jonathan Kodjia and Jordan Ayew - a 90th-minute penalty - either side of Yann Kermorant's equaliser, sealed Aston Villa's win at the Madejski Stadium, and lifted them three places to 17th.