The Scottish boss was named as Sam Allardyce's replacement last month.
The former Everton and Manchester United manager was confirmed as the new Black Cats boss last month after Sam Allardyce left to manage England.
He will be keen to make a positive impression at the Stadium of Light following his disappointing spells with Real Sociedad and Manchester United in recent years.
Sunderland manager David Moyes before the match
Much will rest on how quickly the current group can adapt to his methods, but Defoe believes good things are on the horizon.
“The manager’s been great to be honest,” he told the Chronicle.
“I know people always say that but he’s been good, training’s been really good. He does a lot of possession; he wants us to improve every day. Only positive things can come out of doing stuff like that.”
Sunderland manager David Moyes
It remains to be seen if Moyes can be a success with Sunderland this season.
The signings he can get done before the end of the transfer window will likely be crucial to their hopes, with the current squad short in several areas.
Another striker is desperately needed if they harbour ambitions of being more than relegation battlers, as it would be unwise to rely on veteran Defoe to get the goals they need once again this season.
Sunderland's Jermain Defoe