1. Lack of rhythm in final third without Payet and Lanzini
Both Dimitri Payet and Manuel Lanzini were influential last campaign and when they're missing it's hugely evident, which may cause concern for manager Slaven Bilic. In the first half it seemed as though the Hammers lacked any imagination with no one willing to be the man to force the issue and create something.
Fans' favourite Payet lit up the Premier League in his debut campaign in England with his flamboyant and free flowing approach, his stunning goals from distance, free kicks and assists while Lanzini contributed in being the link man from the midfield to attack along with his team-mate Payet.
The first half especially seemed rather tame and lacked invention from any of the attacking players, which made more evident the effect these two players have on this evolving West Ham side, you do wonder if any of the two got injured across the season would they be able to cope?
2. Ayew signing is a must
Manager Slaven Bilic confirmed live on BT Sport prior to the game against Juve that the signing of Andre Ayew is imminent with the deal being nearly done.
Despite striker Andy Carroll grabbing a brace, it was clear to see they need another dimension to their game. During spells for the 55 minutes he was on the pitch, his team-mates struggled to find the forward. With Ayew's pace he is able to stretch the game, the forward has the ability to go short and receive the ball as well as working the channels which may have caused Juve problems if he was on the pitch.
No doubt the forward issue is alarming and with Diafra Sakho looking likely to leave the club, they're certainly vulnerable in the forward positions. Ayew will be the perfect replacement and someone who will flourish under the playing style of Bilic.
3. Centre backs or no centre backs?
The first half defending at times was shambolic, the pair of Ogbonna and Reid were getting pulled apart with Mandzukic dragging the two into positions they clearly weren't comfortable in.
It's a position that Bilic may not prioritise at this minute given shortages in other areas, however taking into account Europa League football will they need to strengthen in that area? Reece Burke and Reece Oxford looked assured and ready while James Collins seemed to add experience and know-how, but would Bilic give one of the youth products a chance in the side if needs be?
4. Is Sam Byram the answer?
The injury to Aaron Cresswell was a huge blow to West Ham. The full-back signed in 2014 has been a revelation since his transfer from Ipswich Town under Sam Allardyce and has developed into one of the most accomplished left-backs in the league.
The club have had bids rejected for the likes of Jonas Olsson and Andrew Robertson to replace him although Bilic confirmed before the game the club are close to signing Olympiakos full back Arthur Masuaku but after solid performances in his previous two outings can Byram fill the void?
The former Leeds United man has shown in recent games he is able to play on the left and given the fact he's had time to bed in he could be Bilic's choice for next Monday's game at Stamford Bridge.
5. Could youth have a chance this season?
Given the influx of games West Ham could potentially face this season, with Europa League commitments, it may lead to Bilic being bold enough to give some of the club's youth products a chance to play.
With just over 48 hours to prepare for the Juve game it meant Bilic finished the match with eight players under the age of 21 including the likes of Domingos Quina, Lewis Page, Reece Burke, Reece Oxford and Martin Samuelson. Certainly food for thought for the manager as the season progresses.