And now all eyes are on their big move to the 60,000 seater Olympic Stadium down the road in Stratford.
The stadium transformation has been moving at a pace in recent months and supporters are eager to get a first proper look at their new home come Thursday.
But any fears fans may have about the move have been allayed by one of Slaven Bilic's new summer signings Ashley Fletcher.
West Ham's Ashley Fletcher in action in pre-season
'I cannot wait'
The former Manchester United striker told West Ham's official website he cannot wait to get started at the Olympic Stadium after being surprised on his first visit there.
“The stadium is looking great and I cannot wait to play the first game here," Fletcher told whufc.com.
The Olympic Stadium
“I have obviously seen a lot of pictures of the new stadium but you don't appreciate how big it actually is until you come here and I think it is one of the best stadiums I have ever seen.
“Looking at the seats and the scoreboard it gives a real modern vibe and I cannot wait to play my first game here.
“This really shows the level that West Ham want to be aspiring to and was one of the main reasons I joined the club.”
Juventus' goalkeeper Gianluigi Buffon is on his way to East London this weekend
Europa League and Italian giants first up
The Hammers will opening the ground with the second leg of their Europa League third round qualifier against Slovenian side NK Domzale on Thursday night.
Bilic's side trail 2-1 from the first leg and will start life at the new ground under pressure to turn the tie around and remain in European competition.
Domzale may be an underwhelming start to life in the Olympic Stadium, but official opening match comes against Italian and European giants Juventus on Sunday ahead of the new Premier League campaign.
West Ham have sold 52,000 season tickets for their new ground, the second most in the Premier League behind Manchester United.