The Celtic striker admits he feels sorry for the much-maligned defender.
Celtic lost 3-1 to Barcelona in Dublin yesterday, but Brendan Rodgers's side hardly helped their cause by making a series of seemingly costly errors.
One of those came on the half-hour mark as Ambrose diverted a nothing cross beyond his own goalkeeper Craig Gordon to put the Spanish giants 2-1 up.
There was no Barcelona player around to get on the end of the cross, and Griffiths, who scored Celtic's goal, feels that somebody in a green and white shirt should have given the Nigerian a shout to let him know there was no imminent danger.
The Celtic fans in attendance allegedly reacted by booing the much-maliged 27-year-old, whose previous errors have made him something of a scapegoat by the supporters, and the Scotland international admits that he feels sorry for his team-mate.
“It’s just one of those things. If someone shouts behind Efe to leave it, then Craig Gordon has an easy catch," he said via The Scottish Sun.
“Nine times out of ten the ball goes behind for a corner or into the crowd, but Efe’s always the fall guy. It’s these kind of mistakes that are costing us, though
“I feel sorry for him. He wears his heart on his sleeve and he’s a great player. We see it in training all the time."
Ambrose is expected to be back in the first XI next week when Celtic host Astana in the second leg of their third-round Champions League qualifier.
As it stands, Rodgers's side, who drew 1-1 in Kazakhstan, are heading through on away goals, but the Hoops will need to make sure of it at Paradise.