The Celtic defender was seemingly booed in Dublin on Saturday.
Celtic lost 3-1 to a Barcelona side including the likes of Luis Suarez, Lionel Messi and Arda Turan in the Irish capital yesterday.
The Spanish giants went 2-1 ahead on the half-hour mark when the much-maligned Ambrose poked a cross past goalkeeper Craig Gordon, when there was no Barcelona shirt around to convert the ball.
The Celtic fans reacted by allegedly booing the 27-year-old centre-half, who has long been ill thought of within the fanbase for a series of errors down the years - many of which came in competitive outings.
Rodgers has insisted that he did not hear the Nigeria defender suffer any verbal abuse from the terraces, but the Northern Irishman has said that it's simply not nice if it did happen.
“If it was that, I didn’t hear that myself, it’s not nice," he said via The Scottish Sun.
“Efe is a man who, whatever his faults are, is a real good guy who gives his all for the club, devotes his life to Celtic.
“He prepares well, he trains well, he doesn’t cheat. He trains every day and he is a man who wants to get better."
Many Celtic fans on Twitter have acknowledged that it was wrong for those at the Aviva Stadium to boo Ambrose, who joined the Hoops in 2012.
Ambrose has been linked with a move away from the Scottish champions, but the player himself distanced himself from the rumours as a little earlier in the week.