Two Manchester City stars feature prominently.
The quarter-final line-up for Euro 2016 will be clear by the end of tonight with the final last-16 matches taking place this evening.
Italy take on Spain at the Stade de France before England face Iceland in Nice. Italy managed to top their group having beaten Belgium and Sweden in the group stages, while Spain narrowly missed out on top spot after they were beaten by Croatia in their final group game following wins against the Czech Republic and Turkey. The winner of their tie will face Germany in the quarter-finals on Saturday.
England will be looking to improve things in front of goal as the pressure has started to mount a little following a group stage which saw them score just three goals, even if there were periods of dominance. They only managed one win and two draws, while their opponents Iceland also managed an identical record - with their dramatic late win over Austria securing their place in the last 16. The prize on offer is a place in the quarter-finals against host nation France.
Here are three players who could have a big say in today's games:
The Manchester City midfielder has been in excellent form for Spain as he has been at the centre of a lot of Spain's good football.
Italy are a very tough side to break down but Silva has the talent to play that final ball that can open up any side, and it would not be surprising if he is pulling the strings should Spain triumph this evening.
There have been plenty of suggestions that he will start this evening after struggling in the opening two games. His pace is a threat but his end product has been lacking - one moment that sticks out was an opportunity he failed to capitalise on against Wales.
There is some pressure on him to deliver this evening and a good performance could only be good for his confidence.
Daniele De Rossi
The middle of the park is going to be an important battle to win. If Italy are to win that then Daniele De Rossi needs to have a good game both on and off the ball, and given that Spain love to have possession his work off the ball could be more important.