The Arsenal midfielder is in the Three Lions squad for the tournaments this summer despite having missed the majority of the season through injury.
There is fierce debate about whether he should be a starter in the team, with the midfield an area where there is strong competition for places.
The biggest concerns are over his fitness, with the player having endured a horrendous injury record over the last few years.
But Merson insists he has to start as he is the only one in the side who can do something out of the ordinary.
"Jack Wilshere has got to play,” he told talkSPORT.
"He is the only one who doesn't give the ball away. He is the only one who looks forward all the time. He goes forward and has got that guile around the box. "He can do something out of the ordinary and that is what you need.”
There is no denying that Wilshere is the most creative force of England’s midfield options, and on form he would comfortably beat James Milner and Jordan Henderson to a place.
More importantly though, and as Merson says, he is the only one who is good at helping the Three Lions to maintain possession.
That could be crucial to their hopes, especially with games likely to be tight at the tournament this summer.