The Portugal defender believes the Tottenham Hotspur star can fire the Three Lions to success at last.
Kane netted 25 goals in 38 Premier League matches this season to win the Golden Boot in what was initially billed as a difficult second season after scoring 31 in 51 in all competitions at club level last term.
This campaign's tally made the 22-year-old the first Englishman to finish as top scorer in the English top flight since Kevin Phillips achieved the feat 16 years ago, and has seen Kane move from breakthrough sensation to one of the most prolific strikers in Europe.
Kane has already racked up five goals from his first 11 caps for the Three Lions and is almost certain to be the spearhead of England's attack at Euro 2016 in France later this month.
Fonte, whose Portugal side face Kane and England tomorrow night, believes that the Spurs star has the quality to drive the Three Lions on to a first tournament success in half a century.
The Southampton defender told the Standard: "England’s performance in qualifying was very impressive — it got all our attention in the Portugal camp. England did a great job to get a perfect record, they have players on fire, especially in attack.
"They are definitely more of a threat than in previous years. We see the firepower they have and what their strikers have been doing. I know everyone talks about England and how they never get it right, but I think this year could be the one.
"Kane has been fantastic. He scores goals, his movement is great. It will be a tough job for defenders to stop him. He can definitely do a good job in the Euros if he is still physically in good shape, which I’m sure he will be. England fans should be hopeful. Anything is possible for them."
England have more goals in their frontline options than they have had for a long time, with Kane, Jamie Vardy, Wayne Rooney, Daniel Sturridge, and Marcus Rashford having netted exactly 100 goals between them for club and country this season.
With Kane likely to lead the line and Rooney to play deeper, Roy Hodgson will have the different attributes offered by Vardy, Sturridge and Rashford at his disposal as England look to move beyond the quarter-finals of a major tournament for the first time in 20 years.