They are all too aware of the striker's fragility after the past couple of years have been blighted by a series of muscular injuries.
Some will have wanted him to have the summer off, so he could have a decent pre-season under Reds manager Jurgen Klopp and be raring to go for the season ahead; probably with that element of anger of being omitted from the squad having managed to get a decent run of games and form together which saw him still finish as the Reds' top-scorer in all competitions.
Instead he has been given the nod by Roy Hodgson. Some will remember all too well the occasions when Sturridge has been away with the England side and come back with an injury. In September 2014 it caused a massive club versus country row and he was not seen in a Liverpool shirt again until January as successive problems kept him in the treatment room.
There are, of course, fears that could happen again. But despite a recent setback - where he missed the Three Lions' friendly win over Australia - his fitness record since February has been solid. He has been managed well by Klopp at Liverpool in terms of game time, even if the forward would like more minutes on the pitch, and is in a position where he can contribute to his country.
He is likely to be behind Harry Kane in the pecking order for the opening game against Russia, and if Wayne Rooney is starting in either an advanced or forward role, Sturridge may have to make do with a place on the bench.
While he will have a point to prove to his manager at international level that he should be in the starting line-up, there will be a hungry Sturridge wanting to prove himself if he does not get the minutes he would like. It could be used to Liverpool's benefit at the start of next season as they look to generate some momentum in the Reds' first full season under Klopp.
Klopp likes to get his players to channel anger into positive performances, which was seen time and again after setbacks following his appointment in October - inspiring wins in big Premier League games and on their road to the Europa League final.
Some decent game time on the field could continue his good form and be a personal boost to the striker himself.
As is mentioned, the big concern is injuries, ideally a summer off would have been just what was ordered prior to pre-season. But an angry or confident, injury-free Sturridge will be something that Klopp will relish working with.