Sheffield Wednesday clash with Hull City at Wembley this weekend.
Wembley plays host as both Championship sides visit the capital aiming to secure a spot in the top flight next season.
It has been 16 years since Wednesday graced the big time, whereas Steve Bruce's Hull are vying for an immediate return following their relegation last season.
Their experience of the Premier League is one of the reasons why the Tigers are favourites to go up, but Bruce's side survived a major scare in the semi-finals.
Having beaten Derby County 3-0 in the first leg, Hull then shipped two goals against the Rams in the second leg, but ultimately hung on.
Consequently, Merson feels that their second-leg performance was indicative of a weakness in the City side, and he believes the Owls will exploit it this Saturday.
"I would've said Hull certainty, but after watching them [in the second leg] I think Sheffield might have that bit extra," he told Sky Sports' Fantasy Football Club podcast about the Owls, who beat Brighton 3-1 over two legs.