The Liverpool left-back is a Seville native and had spent his entire career with the club before moving to Anfield two years ago.
Moreno was born in Seville and joined his local club as a boy, rising up through the youth ranks and the B team to become a first-team regular at the Andalucian club.
Whilst at the Ramón Sánchez Pizjuán, the 23-year-old was part of the Rojiblancos side which won the Europa League in 2014 and he will come up against his beloved former side in their third straight final when they meet with Liverpool in Basel tonight.
Moreno admits that whilst he is obviously desperate to taste success with the Reds, he would not be able to celebrate scoring against his boyhood club even if it was the goal which won the trophy.
The defender told Marca, as quoted by the Mirror: "Even if it was the winner, I wouldn't celebrate. Sevilla is my home, my city, I have friends and teammates there, it was the club that has made me a footballer.
"For many reasons I couldn't and wouldn't celebrate. It might even make me cry with joy and sadness at the same time. It's all going to be very weird.
"I've always said that if Liverpool didn't win the Europa League then I'd wanted it to be Sevilla. Now we've got to this stage, I'd be lying if I said I wanted them to win. I belong to Liverpool and I want them to win with all of my being."
After an encouraging debut season on Merseyside it initially looked as though Moreno would be a bit-part player this term with teenager Joe Gomez being preferred by Brendan Rodgers at left-back in the opening weeks of the season.
However, an unfortunate season-ending injury to the youngster allowed Moreno to stake his claim, and the Spaniard will make his 50th appearance of the campaign in all competitions tonight.