Defender Van Dijk and defensive midfielder Wanyama started the Premier League game at White Hart Lane in North London, and both played for the entire 90 minutes.
Wanyama had a pass accuracy of 83%, won 60% of his tackles, and made three interceptions and two clearances.
Van Dijk had a pass accuracy of 71%, won 50% of his tackles and 100% of his headers, and made two interceptions, 12 clearances and three clearances.
The Saints came from a goal down to get the better of Spurs 2-1, thanks to a double from Steven Davis.
Southampton fans have taken to Twitter to have their say on the performances of Van Dijk and Wanyama against Tottenham at White Hart Lane on Sunday afternoon.
Below are some of the best comments:
VVD had a far better game than Alderweireld today, won literally every duel. Tbf with Virgil duel's are 90-10 not 50-50 #SaintsFC— Jay (@WxrdProwse) May 8, 2016
Virgil with a MOTM performance day after signing a 6 year contract, what a way to mark it. #SaintsFC— š (@Tadicology) May 8, 2016
Imagine a world where Virgil, Mane, Wanyama AND Ronald sign contract extensions and this squad pushes on together next season... #saintsfc— Ben Stanfield (@BenStanners) May 8, 2016
Why would the likes of Wanyama and Mane want to leave us? We are a club on the up! #saintsfc— Phil Smith (@PSmith1994) May 8, 2016
Genuinely think Wanyama is one of our worst players technically. Anything upward of 10 mil and out the door #saintsfc— Oscar Easton (@Ozzyeaston) May 8, 2016