The Sky Sports pundit does not expect lightning to strike twice.
Tottenham Hotspur's 2-2 draw at Chelsea on Monday night confirmed that the Foxes' fairytale title bid had been completed, with Claudio Ranieri's side seven points clear of the Lilywhites with two games to go.
The Italian manager has himself admitted that what his side achieved is most probably a one-off achievement, believing bigger, richer clubs will go back to dominating England's top flight next season and for years to come.
City also have Champions League football to look forward to next season, and Merson believes that such a commitment will take its toll on their Premier League form, backing Ranieri and co to end up finishing 10th.
"If they finish in the top six next year, I'll be flabbergasted. I think they'll finish 10th," he told Sky Sports.
"What they've done is unbelievable, every one of these players has worked their socks off, every single day of the week, every week.
"But they're in the Champions League next year as well, so there's six league games when they'll be more concentrated on that, in my opinion."
It is fascinating to see how Leicester will get on in the Champions League. If they can keep their squad together for the most part, a big ask in itself, they might well ruffle feathers on the continent, too.
They are a hugely tricky side to beat and some of Europe's elite might find that out for themselves next term.