A sucker punch was dealt to Liverpool in the latter stages of the first leg of their Europa League semi-final as Adrian Lopez slotted home in stoppage time to give Villarreal a 1-0 win on the night.
A few eyebrows were raised by the selection of Roberto Firmino ahead of Daniel Sturridge in the starting XI. Jurgen Klopp's selection was almost vindicated when the Brazilian forced a fine save onto the post from Sergio Asenjo.
Joe Allen had an early opportunity saved while Cedric Bakambu hit the outside of the post at the start of the second half, and was brilliantly denied by Mignolet.
It wasn't a bad away performance from Liverpool, but it all depends on the response from this game now going into the second leg at Anfield next week - and they will be hoping to turn things around in order to reach the final in Basel.
Here's how they rated:
Simon Mignolet - Solid save from an effort midway through the first half, fantastic save from Bakambu that deserved to leave the tie all square - 7
Nathaniel Clyne - Recovered the ball well, a lot. Against Denis Suarez he seemed to hold his own quite well, and was rarely got the better of - 7
Kolo Toure - A masterclass in defending in the first half in terms of positioning, blocks, and clearances in the first half, tired towards the end, and was caught out a little by the crossfield ball for the winner. Where it not for that, he'd score higher - 7
Dejan Lovren - Solid, a couple of occasions when he looked a little lost early doors but soon found his feet and covered well for elder centre-back partner at times - 7
Alberto Moreno - One or two times he allowed a ball being played inside him that shouldn't have happened, a lot of fingers being pointed at him for the goal - ought to have scored the chance gifted to him, though I personally think that's doing a disservice to the defender's role - 5
Lucas Leiva - He had an excellent game, I thought. Broke the play up, his passes 99 times out of 100 found a red shirt. Will be a big player in the second leg, no doubt - 8
Joe Allen - Probably should have done better with early opportunity, kept the play ticking over otherwise, but another that looked as if he tired later on in the game - 6
James Milner - Another workmanlike performance from Milner. Can't help but feel that he was the man that missed a main striker more than most as there were a couple of fine deliveries from him in the first half - 6
Adam Lallana - He got through a lot of the dirty work for the Reds, had a ball offside call against him which later saw him hauled down in the penalty area. Did exactly what Klopp wanted him to do - 7
Philippe Coutinho - A couple of occasions he was outmuscled when he came into the middle, barring the odd speculative shot he didn't offer much. Subsequent knowledge of his illness may partly explain that - 5
Roberto Firmino - Won the ball high up the pitch, some frustration with his movement at times but unlucky not to have found the net in the second half - 6
Jordon Ibe - A couple of naive aspects to his play that let him down, he has pace to burn at times and just didn't use it. Personally, thought he had a disappointing half - 5
Christian Benteke - Sent on to close the game out, and maybe even find the net with a speculative effort. Didn't really have much time to have an impact on the game - N/A