Speculation has been rife for months as to who the Hammers would play in the milestone first ever match at their new 60,000 seater home when they leave Upton Park at the end of the season.
The likes of Real Madrid, Barcelona and Bayern Munich were tipped to be in the running.
But now the speculation has been put to bed after the East Londoners announced Juve, who sealed a record fifth consecutive Serie A title on Monday, would be their first opposition at the ground on August 7 via the club's official website.
The Old Lady are one of the world’s biggest and most-successful clubs, with two UEFA Champions League titles, three UEFA Cups and more Serie A titles to their name than any other club.
Excitement at hosting footballing royalty
There has been plenty of excitement at the announcement and the prospect of seeing the likes of Paul Pogba, Gianluigi Buffon and Mario Mandzukic at the Olympic Stadium.
The match, the first ever between the sides, could be the perfect warm-up for the new season as the sixth-placed Hammers are flying high and look likely to at the very least play in the Europa League next season.
Here is a look at how West Ham and Juve fans reacted on Twitter to the announcement and ticket prices which will see Band 1 season ticket holders in the 1966 section charged as much as £50 per ticket.