The Owls lost 2-1 to their Championship rivals in December.
The last time these two sides met, it was Karl Robinson's men that came out on top with a 2-1 victory back in December. But with the Owls flying high in the top six while the Dons are in the Championship's bottom three, Loovens has suggested that it is important for Wednesday to get revenge this time around.
"It wasn't one of our best games so maybe we owe them," he told the Star. "It will be a different game at home. We have been very solid and good at home so hopefully it will be a different outcome.
"It won’t be easy. It is one of their last chances to stay up so we expect a very tough game. They are fighting for their lives."
While the result was not ideal last time, it did provide the club with arguably one of the more defining moments of their season as it was the fixture which saw Gary Hooper's first goal following his loan move from Norwich.
The goal ended a seven-game wait for his first strike for the Owls, and started a run that would ultimately see him score 10 goals in as many league games and persuaded the club to make his move permanent.
And while Carlos Carvalhal's men cannot guarantee their play-off spot on Tuesday, they can take one giant step towards that goal by securing three points and banishing the disappointment from the last meeting between the pair.