The Foxes head into the game having won each of their last five games without even conceding a goal, and last weekend's 2-0 win over Sunderland took them one step closer to the Premier League title after a remarkable season.
That game against Sunderland was seen as a potential banana skin for Leicester, but they passed the test with flying colours - and now they face another clash seen as a game where Claudio Ranieri's side could slip up and allow second placed Tottenham back into the race.
Leicester host West Ham United at the King Power Stadium, with the Hammers on something of a low having lost 2-1 at home to Manchester United in the FA Cup on Wednesday.
The result came off the back of three successive draws for Slaven Bilic's men, who have now conceded seven goals in their last three Premier League goals.
West Ham's bid for Champions League qualification appears to be slipping away, but with the likes of Dimitri Payet and Manuel Lanzini, they could well sprint a surprise and claim a result at Leicester.
Now, pundit Jamie Redknapp has offered his opinion on the game, telling Sky Sports that whilst he predicts that Leicester will win, he wonders whether this is the weekend where the Foxes will slip up, despite claiming that the Hammers are low on confidence and possibly fatigued.
"This game has fallen nicely for them," said Redknapp. "You wouldn't have wanted to play West Ham had they beaten Manchester United and been full of confidence. They're maybe on their knees at the moment, they're lacking a little confidence after that, they didn't play well against Manchester United. It might be a game too far, they might start feeling a little bit tired, a bit fatigued."
"For Leicester, this is a really good time to play West Ham after a really tough FA Cup game in midweek. I do think Leicester will win it, but you just get that feeling that something might happen, this could be the weekend for it to happen," he added.
What's your prediction for Leicester v West Ham?