The game could have major implications at the bottom of the Premier League.
The contest at Carrow Road pits the side just above the bottom three against the team directly below them, so could provide a huge indication as to who will be relegated from the Premier League this season.
The Canaries have the opportunity to go seven points clear of their opponents should they win, while the Black Cats could move to within one point of Alex Neil's men with the added bonus of a game in hand to potentially move themselves away from danger.
And Nicholas suggested that the pressure of playing at home may ultimately do Norwich more harm than good against Sam Allardyce's men.
"Norwich are vulnerable at the back, especially with Timm Klose being injured, which is a real blow for them, and I think they'll push on and attack because of the crowd and that might just suit Sunderland," he told Sky Sports.
If Klose does not play, it would be a big blow to the Canaries' chances of securing a vital win. The defender has been fantastic since he has settled in England, helping the side concede just three goals in their last four games and keep clean sheets against Manchester City and West Brom.
And if Sunderland are capable of taking their chances, then it may prove to be an afternoon that makes the relegation picture seem a little more blurry.