The Royals will take on Leeds away from home at Elland Road in the Championship on Saturday afternoon.
McDermott, who was in charge of the West Yorkshire outfit from April 2013 until the end of the 2013-14 season, has sung the praises of the Leeds supporters.
“I don’t think I did enough there or was there long enough to expect anything of anyone,” the Reading boss told The Yorkshire Evening Post when asked about the reaction he will get from the Leeds fans at Elland Road on Saturday.
“The supporters are tremendous, fantastic people, but there’s no reason for the crowd to give me a good reception.
“I did my best at that time and I think that’s all you can ask. It wasn’t easy. Things went on there that I’ll probably never experience again. But I’m looking forward to going back.”
Reading are 14th in the Championship table at the moment with 51 points from 41 matches, level on points with Leeds, who are a place below them in 15th.
Leeds will fancy their chances of winning against the Royals, especially as they are at home.
The Whites will head into the match on Saturday afternoon on the back of a 2-1 victory over Birmingham City away from home at St. Andrew’s Stadium in the Championship.
Reading lost to Middlesbrough 2-1 away from home at the Riverside Stadium in the league on Tuesday evening.