The BBC pundit believes Jurgen Klopp will select the young Belgian against Borussia Dortmund.
The Reds take on Klopp’s former team at Anfield on Thursday, with the tie level at 1-1 following the first leg in Germany last week.
He has something of a selection dilemma for the game, with both Origi and Sturridge vying for the striker’s position.
The young Belgian did not do his chances any harm with two goals in the 4-1 win over Stoke on Sunday, and Sinclair feels he may get the nod for the Europa League clash.
“It’s a great problem to have, two strikers in form. I think he [Klopp] will want to play with one,” he told Match of the Day 2.
“Probably where Origi has the edge on Sturridge is his work rate. He gets back in and helps the team out a little bit more than Daniel.
“For me, for the second leg against Borussia Dortmund, he probably will get the nod for that reason.”
That work rate that Sinclair mentions could definitely be the crucial factor in who gets the nod for the game against Dortmund this week.
The Reds will need their whole team in their best form in the game, with any weak links in the side sure to be exploited by the dangerous Germans.
Origi has already proved he can do his defensive duties in the first leg, and given his display against the Potters he is likely ahead of Sturridge in the pecking order at present.