Speaking to Sky Sports in Italy, Szczesny praised the Foxes, describing their season as a miracle:
"No one in football can explain the Leicester miracle. Even though I support Arsenal in the Premier League, I'd like to see Ranieri's side win it. They're an example and an inspiration to everyone. It's exciting to watch them play."
The 25-year-old Pole's attitude was often questioned in north London and these latest comments will do little to endear him to the Emirates faithful.
He has conceded 45 goals in 35 games for Roma this season, with many of his performances being called into question.
With Petr Cech now manning Arsenal's goal, and David Ospina in reserve, it is highly unlikely Szczesny would get any game time at Arsenal next season - and a deal to move him on would suit both parties.
He is also struggling to make Poland's starting eleven for Euro 2016. Szczesny lost his starting spot to Artur Boruc last year and has since failed to regain it.
With these latest comments, Szczesny may have signalled the end of his Arsenal career - one that promised so much but delivered little.