The Reds played out a 1-1 draw with the Bundesliga giants in the first leg of their quarter-final clash at Signal Iduna Park.
Divock Origi scored the opening goal of the game in the 36th minute before spurring a glorious chance to put Liverpool two up on the stroke of half-time.
The Premier League side were made to pay for that miss as Mats Hummels made them pay following the interval, heading past Reds goalkeeper Simon Mignolet three minutes into the second period.
Jurgen Klopp was given a rapturous welcome by the Dortmund supporters in his first return to the club where he spent the previous seven years.
Famous for their raucous support and ‘yellow wall’ of fans, Dortmund are regarded as possessing the most audible fans in Germany - and that was certainly on show in Thursday’s European tie.
Croatia international Lovren, who enjoyed a strong performance to deny prolific striker Pierre-Emerick Aubameyang, admitted after the game to BT Sport he struggled to communicate with his team-mates due to the volume inside the stadium.
"It was a great job from everyone today. We had great discipline in defence from all 11 players,” the defender was quoted as saying by Goal.
"It was noisy, we couldn't hear each other, but it was a great defensive performance for us."