The midfielder has not featured for Arsenal this season, but could be in Roy Hodgson's plans.
The midfielder has not played a single minute of football this season, having picked up an injury on the eve of the campaign.
He is fighting back to full fitness though, and could make his return just before the Three Lions head to France for the tournament.
There is currently widespread debate about whether he should be part of the squad, having played a big role in the qualifying stages.
And Merson believes he should be taken as he offers the side something different from what they already have.
“One thing about Roy is he is very loyal. He's very loyal to the people who have helped in along the way in the group stages,” he told Sky Sports.
"If he's fit I think he will take him, I think he's different to what we have got. He will make things happen, and sometimes you've just got to take that chance."
"There are 22 players. If he breaks down halfway through the tournament, there has got to be someone else to step in.”
The biggest issue that many would raise in selecting Wilshere is that it would come at the expense of someone more deserving.
That player would be someone like Mark Noble, who has impressed in the heart of West Ham’s midfield this season but has not been given his chance on the international stage.
Many regarded that as a mistake, and picking a half fit Wilshere ahead of him for the tournament could prove to be another one, despite what Merson says.