Rio Ferdinand has told BT Sport, broadcast on March 15 at 9.45pm, that the whole of the Manchester City squad could suffer after Vincent Kompany picked up a calf injury against Dynamo Kiev.
During the early stages of the Champions League last-of-16 fixture at the Etihad Stadium, Kompany grimaced as he attempted to clear the ball and fell to the ground knowing that he had suffered a recurrence of a problem that has plagued him this season.
He was immediately replaced by Eliaquim Mangala as he made his way down the tunnel, and moments later, his central-defensive partner Nicolas Otamendi followed him after also picking up a fitness issue.
However, it was the injury sustained by Kompany that Ferdinand sees as a pivotal moment, and he has suggested that the confidence within the team may drop without their captain in the starting lineup.
The former Manchester United player said: "What it does is take away a bit of confidence from the other players. He is the mainstay in this team and the guy that they look to for confidence when it goes beyond their midfield and it's him cleaning up.
"The record that they have without him is very worrying when you consider the rest of the season. He's not a player that just has to play well himself, but his presence being there enables other players to play better. It gives them the confidence to perform."
City managed to see out the second leg of the tie by registering a goalless draw against Kiev, giving them a 3-1 success on aggregate.