Rose has never played for England but has been called up in the past, Trippier has never received a call-up.
The likes of Harry Kane, Kyle Walker and Dele Alli are all likely to be in the squad - but two other players may also get a nod, with hope of making their England debuts.
Rose has been called up to England duty before but has not yet made his international debut - but at the moment he must be in with a shout.
The defender has come on leaps and bounds this season. He has improved on his defensive frailty and is surely now on the cusp of England recognition.
Luke Shaw is injured. Leighton Baines has struggled for form at Everton, as well as carrying a long-term ankle problem. Meanwhile, at Arsenal, Kieran Gibbs is the back-up to Spanish star Nacho Monreal.
Other options are Ryan Bertrand and Aaron Cresswell of Southampton and West Ham respectively but Rose is currently starring at left-back for a team battling for the Premier League title so should certainly be considered for a call-up.
Trippier has been, for the large part, the second choice right-back at Spurs this season behind fellow England hopeful Walker. His inclusion would come as more of a surprise - considering Liverpool's Nathaniel Clyne is also in the reckoning.
But it may be Hodgson simply wants to take a look at yet another full-back option before Euro 2016.