Gary Rowett's men take on the Tigers on Thursday night at St Andrew's.
Steve Bruce's side are currently second in the Championship, and the game at St Andrew's presents them with the opportunity to move back to the top of the table. And while it was the Tigers who came out on top when the two sides met in October, Morrison insisted that the Blues can upset the high-flyers.
"It's a big game," the defender told the Mail.
"You want to get points on the board. I don't think it makes or breaks the season but certainly we want to get back to winning ways.
"The game up there was quite a while ago now. We know they are a good team but we have evolved from then, we know we can cause them problems.
"We have been good at home of late and hopefully we can take that home form into that game."
As well as looking to dent Hull's automatic promotion hopes, Gary Rowett will be looking for his side to get their own play-off ambitions back on track.
Birmingham are four points off the top six - although, they do have a game in hand over Sheffield Wednesday, who occupy that final play-off spot - and their current run of form suggests that a positive result against Hull is almost a must if they hope to remain in the promotion picture.
They have won just once in their last five games, and that victory came against relegation candidates Bolton, so losing more ground may severely dent their confidence to the point that they get dragged into the mid-table pack.