The Black Cats forward was poor on Saturday afternoon.
Indeed, Dublin feels Sunderland have been poor of late and is concerned for their survival chances.
Were he a supporter on Wearside, however, the pundit would pin his hopes on the goals of Defoe...
Dublin told the BBC before Saturday's game: "It’s a tall order, Sunderland have been poor, there has been a run of games where they have seen a bit of light that they may be able to drag themselves out of that bottom three.
"Get the ball into areas you hope Defoe is going to be. He is their only chance of getting out of the bottom three. He’ll score goals if he gets the chance."
The Sunderland striker's performance at Upton Park, though, was a disappointment to anyone pinning their hopes on him.
Dublin may well be right but that doesn't bode well if the 33-year-old continues to miss chances like he did on Saturday.
Everyone has an off day, of course, and Defoe will be looking to bounce back when the Black Cats host Crystal Palace on Tuesday night.
That is a far more winnable game for Sam Allardyce's men and all eyes will be on the club's forwards to produce some goals.