The two sides meet at Old Trafford on Sunday afternoon.
The two sides meet at Old Trafford on Sunday, with United keen to avenge the 3-0 defeat they were subjected to at the Emirates earlier in the campaign.
They come up against an Arsenal side who are vying for the Premier League title and keen to bounce back after a disappointing midweek loss to Barcelona in the Champions League.
And Coquelin says United would consider it a big win if they were to beat his side.
“It would be a massive win for them to beat us. But we’re going to be ready,” he told Arsenal.com
“We beat Leicester and I think the whole team is conscious that, if we want to win the title, we have to win against these kind of teams.”
“We’ve just beaten the team at the top of the league and shown that we have the desire to do well and grab silverware at the end of the season.”
Those comments from Coquelin go to show just how the two sides’ fortunes have flipped in recent years.
Not too long ago it was Manchester United who were challenging for the title under Sir Alex Ferguson while Arsenal were the ones struggling to secure a place in the top four.
Instead, the Gunners are now title challengers, and favourites for some, while United continue to struggle under Van Gaal’s leadership.
Similarly Wenger’s side are the bookmakers favourites for the game despite not having won at Old Trafford since 2006, another indication of the reversed fortunes of both clubs.