Stoke will take on Villa at the Britannia Stadium in the Premier League on Saturday afternoon.
Former Liverpool defender Lawrenson has backed the Potters to pick up all three points from the encounter courtesy of a 2-0 victory.
“I find Stoke a very difficult team to predict, unless they are playing Aston Villa - you have got to predict everybody to beat them," the former Republic of Ireland told BBC Sport.
Stoke are 10th in the Premier League table at the moment with 36 points from 26 matches.
The Potters will head into the game against Villa as favourites and will be expected to win.
Villa have shown some positive signs in recent weeks, but Remi Garde’s side are likely to come up short at the Britannia Stadium.
The Villans will head into the match against Stoke on the back of a 6-0 defeat to Liverpool at Villa Park in the Premier League.
The Potters won 3-1 against Bournemouth away from home at the Vitality Stadium in the league in their last competitive game.