The Baggies actually took the lead at the Madejski Stadium, as Darren Fletcher opened the scoring - but that's as good as it got for West Brom in a miserable afternoon.
Former West Brom defender Paul McShane scored against his former club to equalise, before Chelsea loanees Michael Hector and Lucas Piazon notched to seal a 3-1 win for Brian McDermott's men.
The defeat once again piled the pressure on manager Tony Pulis, with fans clearly growing more and more disgruntled with the club's current direction.
With just one win in the last six Premier League games, an embarrassing cup exit and a turgid brand of football, it seems that Pulis' time in charge at The Hawthorns is coming to an end.
Fans took to Twitter after the final whistle to make it clear that the clock is ticking for Pulis, and they want him gone either at the end of the season or immediately.
Supporters also suggested that David Moyes or Brendan Rodgers should be targeted as potential replacements for Pulis when he does go, with fans clearly unhappy right now.
Here are some of the reactions from West Brom after losing 3-1 to Reading on Saturday afternoon...
Something has to give- for me pulis can go now or the end of the season as long as we bring the right man in #wba— Steven Massey (@ste198t2) February 20, 2016
Getting increasingly agitated at having Pulis associated with #wba. He is not 'Albion'. And I simply don't trust him.— Steve (@pennwba) February 20, 2016
I respect what Tony Pulis does for teams but if Moyes or Rodgers were interested you'd have to take one of them after today #wba— Colm Brosnan (@ColmBrosnan) February 20, 2016
#wba spent 3 hours on Twitter waiting for the news Pulis has been sacked. Very disappointed not to have heard anything by now.— Jb73 (@Baggie73) February 20, 2016
Sounds like Pulis’s knows his time is up. Hope the next appt is football minded, and given funds to strengthen squad. #wba— Spencer George (@uber_foods) February 20, 2016
Everything that is going wrong is coming back to Pulis, poor performances and fans fighting amongst themselves a result of that Imo #wba— Andi Purewal (@AndiPurewal) February 20, 2016
I'd say Pulis has just blown his last chance of keeping the last of the supporters on side. He has to go #wba— Chris Griff (@GriffGoesBoing) February 20, 2016
Only positive is every loss brings us closer to pulis going in the summer #wba— Christopher Edwards (@SonOfApathy) February 20, 2016
That being said, even more disgusted with the performance. Pulis is poisoning the players, performances and fans. Time to go #wba— Hannah (@han_baggie) February 20, 2016
Todays farce on and off the pitch,reminds me of the dark days of Bobby Gould.Pulis has ripped the heart and soul out this club.#wba— Michael whitehouse (@Michaelwh24) February 20, 2016
Do you think it's time for Pulis to leave West Brom?