Manager Manuel Pellegrini has said in his pre-match press conference, reported by Manchester City's official website, that he has just 13 first-team players available for the FA Cup tie with Chelsea.
In recent weeks, Pellegrini has seen several players join the growing injury list at the Etihad Stadium, with Kevin de Bruyne and Samir Nasri already considered long-term absentees.
With City scheduled to face Dynamo Kiev in the Champions League on Wednesday, that has resulted in the Chilean boss selecting a weakened squad for the trip to Stamford Bridge on Sunday afternoon.
However, Pellegrini has suggested that it is the perfect platform for the club's young talent to showcase their ability as they bid to impress among some of European football's elite players.
Pellegrini said: "We have just 13 players available to play - we have to play Champions League on Wednesday - we’ll see the best team we can play on Sunday.
“We couldn’t play on the Saturday for some reason, so we put out the best team we can.
“Young players have the option and they must take their chances. We normally have some young players in the cup - one or two maximum. I hope with the team we play against Chelsea, we hope they make the performance that we know they can.”
City need a positive result in West London to maintain their bid for the quadruple, but it comes as no surprise that Pellegrini has appeared to place priority with the Champions League.
The club have not reached the last eight of a European competition since their run to the UEFA Cup quarter-finals in 2009.