The American youth international will be hoping to make his debut in Florence.
Spurs are still competing on three fronts, with the Premier League in sight as well as the FA Cup and the competition they will be playing in tomorrow. So changes might be likely in the Spurs line-up for the game, indeed, French number one goalkeeper Hugo Lloris has been left at home.
The game may in fact present an opportunity to young American Cameron Carter-Vickers - who trained with the first-team yesterday.
Carter-Vickers was fully in the action with the rest of the Spurs players after getting a bump up the squad placings after Federico Fazio was loaned out to Sevilla.
Born in Southend the 18-year-old already has the build of a 30-year-old man and has impressed with the United States under-23 side and the Spurs under-21s.
The Tottenham talent will hopefully impress when he does get his chance at Spurs - but the Fiorentina clash might still have come too soon.