Brazilian playmaker Coutinho missed a month of action at the start of the year with injury before making a goalscoring return in the FA Cup defeat to West Ham earlier this month.
Meanwhile, England striker Sturridge has managed just six Premier League appearances this season but also scored on his comeback from a spell on the sidelines in the 6-0 rout of Aston Villa last weekend.
The forward's Three Lions teammate Clyne had high praise for the star duo and said that their importance to the club should not be underestimated.
He told the Echo: "Sturridge and Coutinho are both quality players. They are massive for us. They can get us goals and offer a real attacking threat.
"It is good to have them back and you can see the difference their quality makes to us. I am sure they are hungry and fresh for the rest of the season.
"We had a lot of injuries during a difficult period and lost quality players at an important time. But we have got a lot of them back now and hopefully we can push on for the rest of the season. We want to build up our momentum."
Were it not for the defeat to the Hammers earlier this month, Liverpool would still be competing on all fronts.
Their league campign, however, needs some improvement if they are to requalify for Europe, with the Merseyside club currently down in eighth.