Wayne Rooney had already been ruled out of Midtjylland tie but reports now suggest he will miss up to two months.
However, it now appears as though the damage could be worse than first thought, and the report claims that player, club, and country are concerned that the forward could miss up to two months of a crucial period.
The Red Devils also have FA Cup and European campaigns to contend with, meaning that a busy fixture schedule is likely over the next few weeks, a period they would be desperate to have Rooney available for.
Meanwhile, England boss Roy Hodgson would want his captain fit for the upcoming friendlies against Germany and the Netherlands, and will be concerned at any lengthy lay-off with Euro 2016 around the corner in the summer.
Rooney has been criticised in some quarters for a perceived dip in form this season, but he has still made an important contribution to United’s season, netting 14 goals in 32 matches in all competitions, already matching his tally from last term.