Ryan Giggs will reportedly turn down the chance to take over as caretaker boss again.
The Welshman is thought to be reluctant to merely fill in as caretaker manager for a second time at Old Trafford in the event of Louis van Gaal's exit from the club.
With former Chelsea boss widely thought to be the frontrunner to take over from the Dutchman, United could lose Giggs from their coaching staff, with the former midfielder harbouring managerial ambitions of his own.
Giggs, who played nearly 1000 games for United in a 24-year professional career with the club during which he won 13 Premier League titles and two Champions League trophies, does not want to continue playing second fiddle on a long-term basis.
The 42-year-old previously filled in as caretaker manager following the sacking of David Moyes in April 2014, winning two and drawing one of his four matches in charge at the end of the season.
Louis van Gaal was ultimately appointed as Moyes' permanent successor, with Giggs moving to an assistant role, but the Mirror claims that the right-hand man believes that now is the time for him to make the step up on a full-time basis.
United are currently fifth in the Premier League table, six points behind neighbours Manchester City in the race for a Champions League spot.