Sunday's clash at the Etihad will see two of the top four sides in the Premier League come up against each other.
Kieran Trippier has admitted to Tottenham's official website that it will be a big challenge for them to go to the Etihad Stadium and get a positive result against Manchester City, but insisted that Mauricio Pochettino's side are optimistic about their chances.
Two of the Premier League's top four meet at Eastlands on Sunday, and Trippier - who began his career with the Citizens - suggested that Spurs are going into the encounter hoping to extend their winning run, which currently stands at six games in all competitions.
"It's going to be a tough test for us at City this weekend, they've got some very good players, but we just need to focus on ourselves. It's been brilliant in training this week, everyone's been buzzing just like usual. We're on a good run at the moment, we've had six games without defeat now so hopefully that can continue," he told the club's official website.
With the former Burnley defender suggesting that spirits are high in the Tottenham team currently, and with the side enjoying such an impressive run of form, Pochettino's men are arguably travelling to face Manuel Pellegrini's side at the perfect time.
City went into last weekend knowing that a win over Leicester City would have seen them go above the Foxes, and reach the summit of the table. However, Claudio Ranieri's side's 3-1 win meant that they now find themselves six points adrift of the league leaders.
And should Spurs make it back-to-back weeks where the Sky Blues have been beaten in front of their own fans by title rivals, then City could find themselves nine points off top spot, which may, at this stage of the season, be too big a gap to bridge.
Meanwhile, another victory would not only extend Tottenham's winning run, but if their North London rivals can also secure three points in their game with Leicester, then Spurs would be within two points of the leaders, and arguably have all the momentum they needed to go on and claim the title.