Sunderland will take on United at home on Saturday afternoon, and Barnes believes that the match will end 1-1.
“Sunderland’s comeback at Liverpool will fill them with confidence,” the former Celtic manager wrote on Titanbet.co.uk. “They weren’t good at Anfield, but results breed belief and at home I think they can get something against Man United. Goalscorers – Jermain Defoe and Wayne Rooney.”
Sunderland are second from bottom in the Premier League table at the moment with 20 points from 25 matches.
Sam Allardyce’s side are four points behind 17th-placed Newcastle and are in real danger of going down to the Championship at the end of the season.
The Black Cats will head into the game against United on the back of a 2-2 draw with Liverpool away from home at Anfield.
Meanwhile, the Red Devils currently find themselves fifth in the league table with 41 points from 25 games.
Louis van Gaal’s side are six points behind fourth-placed Manchester City and are still in the running for a Champions League spot.