The defensive midfielder scored a crucial goal in the 4-1 victory.
Spurs moved up to second in the league with a win against Watford last week, as Manchester City dropped to fourth after a thrashing from current league leaders Leicester City.
The two clubs have already met once this season, when City were put to the sword by Spurs at White Hart Lane in September.
Goals from Eric Dier, Toby Alderweireld, Harry Kane and Erik Lamela did the trick for Spurs, despite going 1-0 down to a Kevin De Bruyne strike in the 25th minute.
The goal from Dier on the stroke of half-time was key, and what a goal it was. The defender converted into a defensive midfielder smashed an instinctive drive from outside the box that whistled into the back of the City net.
Speaking to Tottenham Hotspur's official website today, ahead of the City repeat fixture, he spoke about that goal:
"The first thought that crossed my mind was to stop their potential counter-attack.
“Then I realised I had more time than I thought.
“I thought I was going in for a tackle to begin with but I had the time to get there and strike it. I just thought ‘hit it’ and it went right in the corner. It was perfect."
Dier, whose job is to prevent goals rather than score them, may never score a better goal in his career - or indeed a more crucial one.
That result kicked Tottenham into gear after a stuttering start to the campaign and Spurs fans will be hoping that they can turn over City once again this weekend.