Ince featured in the FA Cup fourth-round tie against Premier League giants United at the iPro Stadium.
The 24-year-old, who is a versatile player and can play as an attacking midfielder, winger or forward, started the game and played for the entire 90 minutes.
The former Liverpool prospect failed to guide the Rams to a win, as United ran out 3-1 victors.
Ince is an important player for Derby, but he has not been at his best for Paul Clement’s side so far this season.
The former Hull City attacker has scored eight goals and created 54 chances in 25 Championship games so far this campaign.
Derby fans have taken to Twitter to have their say on Ince’s performance against United on Friday evening.
Below are some of the best comments:
Credit to @StephenWarnock3 for staying behind from all the players just to applaud the fans.Its a shame shackle and Ince just walked off— Kenny Jones (@kenny_dcfc) January 30, 2016
Tom Ince was about as good as an ingrown toe nail tonight #dcfc— kieran bexon (@kieran_bexon) January 29, 2016
Ince will never make it in the Premier League. That said, neither will any of the squad, bar Hughes and maybe Butterfield. #dcfc— James Capps (@JamesCapps_) January 29, 2016
Disappointed don't mind but never really got @ them Don't know what Johnson & ince need to do to be dropped been dreadful for wks #dcfcfans— Scotty (@Dcfc_s) January 29, 2016