The Sunderland striker has been in fine form for Sam Allardyce's side this season.
The veteran forward has been in fine form for the Black Cats this season, with nine goals in the league to his name so far.
That tally makes him the third highest scoring Englishman in the division this season, behind surprise leader Jamie Vardy and Tottenham Hotspur’s Harry Kane.
And Merson says if he were England manager Roy Hodgson he would take Defoe to Euro 2016 as he’s the national sides most natural goalscorer.
“If he gets ten more goals from now until the end of the season, and Vardy doesn’t score, who do you take?” he told Soccer Saturday.
“I would take Defoe. I would take Defoe anyway. He’s our best natural goalscorer.”
“We don’t make a lot of chances in these tournaments, so you need someone who’s going to be two chances one goal. Defoe scores goals and that’s the hardest thing in the world.”
Given his form for a struggling Sunderland side this season, it would certainly make sense for England to take Defoe to France in the summer.
They are short on regular goal scorers, with Kane and Vardy having impressed but both untested at the highest level and Wayne Rooney struggling to capture his best form for Manchester United.
Defoe would then be a wise fourth choice in that regard, with him adding some much needed goalscoring prowess as well as experience that is lacking from the current international squad.