Afobe left Wolves to join Bournemouth at the start of the month, leaving Kenny Jackett’s side without their top scorer.
Wolves have had to cope with playing two wingers up front since Afobe has left - with Michal Zyro and Rajiv van la Parra being used as their top two.
However, Holloway feels that Wolves will be better off now Afobe as left, as the 22-year-old made no secret of his desire to move to the Premier League.
"Afobe’s move [surprised me]," Holloway said. "He hasn’t been the same player this year as he was last year. He wasn’t even playing a few weeks ago.
"You have to be careful, because your job is to perform and to keep playing.
"You can’t even disrespect your football, and club and I think Wolves will be stronger now.
Afobe was linked with Norwich City in the summer transfer window, but Wolves rejected all approaches for the front man.
After that move fell through, Afobe was not as prolific - and he only netted 10 goals in 27 matches in the first half of the Championship season.
Bournemouth were not put off by the striker’s struggles, however, and their faith has already been rewarded - after the former Arsenal man netted his first goal in the top flight in their last fixture against Norwich City.