Wednesday head into the game having beaten Fulham 2-1 in the FA Cup on Saturday afternoon, whilst they've also been in fine form in the league.
With just two defeats in the last nine Championship games, Carlos Carvalhal's men look like a major contender for the top six this season, and lie just two points away from a play-off place.
Tonight, the Owls take on beleaguered Bolton Wanderers, who are suffering major problems on and off the field this season.
Rooted to the bottom of the table with just 17 points from 25 games having only won twice this season, Neil Lennon's men appear to be heading towards relegation to League One.
Factor in the club's financial problems, and there appears to be little hope for Wanderers, making tonight's game against a club with wealth and quality something of a daunting task for the Trotters.
Speaking ahead of the game, pundit Ian Holloway has told Sky Sports that he thinks this is the worst time for Bolton to be facing Wednesday, predicting a 3-1 win for the in-form Owls, citing their incredible home form so far this season as a major factor.
"It's very sad what's happening at Bolton. They need a buyer, pronto," said Holloway. "I hope someone can save the club as they're in turmoil. This isn't the right time for them to be going to Sheffield Wednesday, especially now they're losing two of their best players in Zach Clough and Mark Davies. Wednesday are unbeaten in 11 games at home, winning eight and have conceded just three goals in their last eight home games. More misery for Bolton, I'm afraid," he added.
What's your prediction for Sheffield Wednesday v Bolton?