Indeed, the Black Cats beat Villa 3-1 and Defoe was allowed enough space to cause some real damage in front of goal.
And, highlighting one of the goals in particular, the pundit took 33-year-old Lescott to task.
Cascarino told Sky Sports News on Monday morning: "He’s go to do better. Jermain Defoe is 32 and Lescott’s made it too easy for him.
"Villa have been poor and, when you’re bottom of the table, people are going to point fingers at you."
Lescott has been in poor form all season but, naturally, he isn't the only one.
Many Aston Villa fans want Jores Okore in at the heart of defence, while there are pleas to send Micah Richards to his natural position at right-back. Neither option was used against Sunderland.
Next up for Villa is an FA Cup third round trip to Wycombe. It can no doubt be viewed as a distraction in the fight against relegation but it may have its advantages.
Should Remi Garde get his side together and playing well against the League Two outfit, a break from the pressure of the Premier League could do Villa good - as well as the chance to build some confidence ahead of their clash with Crystal Palace.