The Gunners head into the clash five points behind Premier League leaders Leicester City and a solitary point ahead of their upcoming rivals, making the encounter very much a must-win one.
City haven’t been in great form of late and are winless in their last four away games, and they face Arsenal missing Vincent Kompany at the back and possibly Sergio Aguero up front.
Writing in his column in the Telegraph, Redknapp said that he feels that the omens are with the hosts and has backed them to send out a message to the rest of the league with a close-fought victory.
“It will be a tight game but I expect Arsenal will beat them and send out a big message to the league,” Redknapp confidently predicted.
“It all depends on the teams, and whether Alexis Sanchez is fit enough to play even a small part, but I can't see City getting anything.”
The big dilemma for Arsenal boss Arsene Wenger is whether to risk Alexis Sanchez or not.
The Chile international forward suffered a hamstring strain in the 1-1 draw at Norwich City last month and was initially ruled out for up to four weeks, but he has been back in training this week.
It would appear he isn’t 100% fit, but he could be in good enough condition to feature and Wenger must decide whether to risk him against City knowing the importance of the encounter.
Head-to-head encounters between title contenders often make all the difference come the end of the season, therefore both managers will probably be satisfied should it end all square.